The National Research Council and Institute of Medicine held a symposium to explore the health, policy, and ethical implications of direct-to-consumer genetic testing. In the second of four parts, participants focused on regulation of genetic and genome testing. Among the issues they addressed were monitoring and oversight of laboratory and direct-to-consumer procedures, possible roles for federal and state agencies in regulating testing, quality assurance methods, and providing room for future market growth. They also responded to questions from the audience.